339532-12-6
Chemical Structure
T 162559
- CAS No.: 339532-12-6
- Formula:C20H28FN5O6S2
- Molecular Weight:517.59
IUPAC Name: (S,E)-2-(7-(5-fluoro-2-methylphenyl)-4-methyl-7,8-dihydroquinolin-5(6H)-ylidene)hydrazine-1-carboximidamide dimethanesulfonate
InChIKey: RSOZXFHMJJXYKO-APKQPWHZSA-N
SMILES: CS(=O)(O)=O.CS(=O)(O)=O.CC1=C([C@@H]2C/C(C3=C(C)C=CN=C3C2)=N\NC(N)=N)C=C(F)C=C1
Biological Activity: T 162559 is a potent and selective inhibitor of the Na+/H+ exchanger isoform NHE1 with IC50 values of 0.96 nM. T 162559 does not affect Na+/HCO3- cotransport and Na+/Ca2+ exchange. T 162559 can be used for the research of cardiovascular disease[1].
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T 162559 | T 162559 is a potent and selective inhibitor of the Na+/H+ exchanger isoform NHE1 with IC50 values of 0.96 nM. T 162559 does not affect Na+/HCO3- cotransport and Na+/Ca2+ exchange. T 162559 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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Keywords
