4630-95-9
Chemical Structure
Prifinium bromide
- CAS No.: 4630-95-9
- Formula:C22H28BrN
- Molecular Weight:386.37
IUPAC Name: 3-(diphenylmethylene)-1,1-diethyl-2-methylpyrrolidin-1-ium bromide
InChIKey: UCGJZJXOPSNTGZ-UHFFFAOYSA-M
SMILES: CC1[N+](CC)(CC/C1=C(C2=CC=CC=C2)\C3=CC=CC=C3)CC.[Br-]
Biological Activity:
Prifinium bromide is an anticholinergic drug with anticholinergic and antispasmodic activities, and it exhibits oral activity. Prifinium bromide competitively antagonizes cholinergic receptors and relieves symptoms of spasm or hypermotility in the digestive and urinary tracts, with its anticholinergic activity representing the core mechanism underlying the inhibition of bladder smooth muscle contraction. Prifinium bromide can be used in research related to spasms and diverticular disease[1][2][3].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Prifinium bromide | 99.41% | Prifinium bromide is an anticholinergic drug with anticholinergic and antispasmodic activities, and it exhibits oral activity. Prifinium bromide competitively antagonizes cholinergic receptors and relieves symptoms of spasm or hypermotility in the digestive and urinary tracts, with its anticholinergic activity representing the core mechanism underlying the inhibition of bladder smooth muscle contraction. Prifinium bromide can be used in research related to spasms and diverticular disease. |
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- [1]. Terai T, et al. Effects of the anticholinergic drug prifinium bromide on urinary bladder contractions in rat in vivo and in guinea-pig in vitro. Arzneimittelforschung. 1991;41(4):417-420. [Content Brief]
- [2]. Ohki S, et al. Synthesis of Pyrrolidine Derivatives with Pharmacological Activity. XII. Synthesis and Anticholinergic Activity of 1,1-Dialkyl-3-diphenylmethylene-2,4-dimethylpyrrolidinium Halides. Chem Pharm Bull. 1986;34(9):3606-3613. [Content Brief]
- [3]. Sasaki D, et al. Anti-spasmodic effect of prifinium bromide on the proximal and distal colon in patients with diverticular disease. Gastroenterol Jpn. 1981;16(4):344-349. [Content Brief]
Keywords
