47487-05-8
Chemical Structure
KT-1
- CAS No.: 47487-05-8
- Formula:C16H22N4O6
- Molecular Weight:366.37
IUPAC Name: 5-((6,7,8-trimethoxyquinazolin-4-yl)amino)pentyl nitrate
InChIKey: XEMQGFBCRICHHG-UHFFFAOYSA-N
SMILES: COC1=C(C(OC)=CC2=C(N=CN=C12)NCCCCCO[N+]([O-])=O)OC
Biological Activity: KT-1 is a vasodilator. KT 1 can decrease aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increase aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs. KT-1 can be used for the research of cardiovascular disease[1].
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KT-1 | KT-1 is a vasodilator. KT 1 can decrease aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increase aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs. KT-1 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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Keywords
