5948-75-4
5948-75-4
Chemical Structure
gp120-IN-1
- CAS No.: 5948-75-4
- Formula:C15H18N2O4S
- Molecular Weight:322.38
IUPAC Name: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
InChIKey: PXLULCMFZZNMDQ-UHFFFAOYSA-N
SMILES: CCOC(C1=C(NC(NC1C2=CC(OC)=C(C=C2)O)=S)C)=O
Biological Activity: gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 µM and CC50 of 100.90 µM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells[1].
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gp120-IN-1 | gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 µM and CC50 of 100.90 µM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells. | |||||||||||||||||||||
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References
Keywords
