737791-20-7
Chemical Structure
LY550410
- CAS No.: 737791-20-7
- Formula:C20H16N4
- Molecular Weight:312.37
IUPAC Name: 4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
InChIKey: AOTADNCHLKUEAX-UHFFFAOYSA-N
SMILES: C12=C(C3=C4N(CCC4)N=C3C5=CC=CC=N5)C=CN=C1C=CC=C2
Biological Activity: LY550410 is a small-molecule ATP-competitive inhibitor against type I TGF-β receptor kinase, which contains heteroaryl rings for potent binding to the kinase-domain active site. LY550410 modulates TGF-β signalling, thereby regulates gene expression and ultimately cell growth. LY550410 is promising for research of cancers[1].
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LY550410 | LY550410 is a small-molecule ATP-competitive inhibitor against type I TGF-β receptor kinase, which contains heteroaryl rings for potent binding to the kinase-domain active site. LY550410 modulates TGF-β signalling, thereby regulates gene expression and ultimately cell growth. LY550410 is promising for research of cancers. | |||||||||||||||||||||
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Keywords
