799279-67-7
Chemical Structure
C18 LPA
Synonym(s): PA(18:0e/0:0)
- CAS No.: 799279-67-7
- Formula:C21H48NO6P
- Molecular Weight:441.58
InChIKey: FFEGYFZPOUEMED-ZMBIFBSDSA-N
SMILES: O[C@H](COCCCCCCCCCCCCCCCCCC)COP(O)(O)=O.N
Biological Activity: C18 LPA (PA(18:0e/0:0)) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs). It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer.
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C18 LPA | C18 LPA (PA(18:0e/0:0)) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs). It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer. | |||||||||||||||||||||
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