80366-85-4
80366-85-4
Chemical Structure
Boc-NH-O-C1-NHS ester
- CAS No.: 80366-85-4
- Formula:C11H16N2O7
- Molecular Weight:288.25
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 2-(((tert-butoxycarbonyl)amino)oxy)acetate
InChIKey: ZZBOTLREHORFCK-UHFFFAOYSA-N
SMILES: O=C1CCC(N1OC(CONC(OC(C)(C)C)=O)=O)=O
Biological Activity: Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
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Boc-NH-O-C1-NHS ester | 98.0% | Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Boc-D-Leu-Osu | Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S. | |||||||||||||||||||||
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Boc-N-PEG1-C2-NHS ester | 98.0% | Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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T-Butoxycarbonyl-PEG1-NHS ester | T-Butoxycarbonyl-PEG1-NHS ester contains a t-boc protecting group and an NHS ester moiety. T-Butoxycarbonyl-PEG1-NHS ester can be used for the modification and labeling of biomolecules. | |||||||||||||||||||||
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BocNH-PEG2-CH2COONHS | BocNH-PEG2-CH2COONHS ester is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||||||||||||||||||||
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Boc-Met-OSu | Boc-Met-OSu is a Methionine (HY-13694) derivative. | |||||||||||||||||||||
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6-(N-Boc)caproic acid NHS | 6-(N-Boc)caproic acid NHS is a protein cross-linking agent. | |||||||||||||||||||||
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2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate | 98.50% | 2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate (Boc-Beta-Ala-OSu) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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6-(tert-Butoxy)-6-oxohexanoic NHS ester | 6-(tert-Butoxy)-6-oxohexanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. | |||||||||||||||||||||
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Boc-5-aminopentanoic NHS ester | Boc-5-aminopentanoic NHS ester is a linker containing an NHS ester and a t-Boc protected amine group. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | |||||||||||||||||||||
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Boc-Gly-Gly-NHS ester | 97.0% | Boc-Gly-Gly-NHS ester can be used to selectively attach small molecules to specific amino acid residues on proteins, creating conjugates that can be used for a variety of applications in drug discovery and diagnostic assays. | ||||||||||||||||||||
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