847649-50-7
Chemical Structure
8-Bromo-3’-deoxy-3’-fluoroguanosine
- CAS No.: 847649-50-7
- Formula:C10H11BrFN5O4
- Molecular Weight:364.13
IUPAC Name: 2-amino-8-bromo-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
InChIKey: DAPLYTKKVZTKEF-YOUMAJLPSA-N
SMILES: OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C(Br)=NC3=C2NC(N)=NC3=O)O1
Biological Activity: 8-Bromo-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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8-Bromo-3’-deoxy-3’-fluoroguanosine | 8-Bromo-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
