858350-62-6
858350-62-6
Chemical Structure
AR244555
- CAS No.: 858350-62-6
- Formula:C23H23ClF2N2O
- Molecular Weight:416.89
IUPAC Name: (1'-(but-3-en-1-yl)-5-chlorospiro[indoline-3,4'-piperidin]-1-yl)(2,6-difluorophenyl)methanone
InChIKey: QKPSTNGNDWHYCH-UHFFFAOYSA-N
SMILES: O=C(N1CC2(CCN(CCC=C)CC2)C3=C1C=CC(Cl)=C3)C4=C(F)C=CC=C4F
Biological Activity: AR244555 is a malate-aspartate shuttle (MAS) inverse agonist with IC50s of 186 nM and 348 nM in human and rat inositol phosphatase (IP) Gq coupling assays respectively. AR244555 has cardioprotective effects[1].
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AR244555 | AR244555 is a malate-aspartate shuttle (MAS) inverse agonist with IC50s of 186 nM and 348 nM in human and rat inositol phosphatase (IP) Gq coupling assays respectively. AR244555 has cardioprotective effects. | |||||||||||||||||||||
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References
Keywords
