878670-63-4
Chemical Structure
RDEA 806 potassium
- CAS No.: 878670-63-4
- Formula:C24H17BrClKN4O3S
- Molecular Weight:595.94
IUPAC Name: 4-(2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)-3-chlorobenzoic acid, potassium salt
InChIKey: ZVIWEYTXPYNLGB-UHFFFAOYSA-M
SMILES: O=C(C1=CC=C(C(Cl)=C1)NC(CSC2=NN=C(N2C3=C4C=CC=CC4=C(C5CC5)C=C3)Br)=O)O[K]
Biological Activity: RDEA 806 potassium is an orally effective non-nucleoside reverse transcriptase (NNRT) inhibitor that exhibits potent in vitro inhibitory activity against wild-type HIV-1 (EC50 = 1.7 ng/mL) and NNRTI-resistant HIV-1. RDEA 806 potassium rapidly reduces HIV-1 RNA viral load in vivo. RDEA 806 potassium has a favorable biosafety profile. RDEA 806 potassium can be used for research related to HIV-1 infection[1].
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RDEA 806 potassium | RDEA 806 potassium is an orally effective non-nucleoside reverse transcriptase (NNRT) inhibitor that exhibits potent in vitro inhibitory activity against wild-type HIV-1 (EC50 = 1.7 ng/mL) and NNRTI-resistant HIV-1. RDEA 806 potassium rapidly reduces HIV-1 RNA viral load in vivo. RDEA 806 potassium has a favorable biosafety profile. RDEA 806 potassium can be used for research related to HIV-1 infection. | |||||||||||||||||||||
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