943790-62-3
Chemical Structure
VIR-165
- CAS No.: 943790-62-3
- Formula:C109H156N22O25S2
- Molecular Weight:2238.67
IUPAC Name: (S)-5-(((S)-1-(((2S,3S)-1-((S)-2-(((6S,9S,12R,17R,19aS,24aS)-17-(((2S,5S,8S,11S,14S)-18-amino-11-(2-amino-2-oxoethyl)-8-benzyl-14-((S)-2-(((S)-1-(((S)-1-(((S)-1-carboxy-2-phenylethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamo
InChIKey: LXXYOCAOYCSKEP-AKMQUIECSA-N
SMILES: O=C1[C@@]2([H])N(CCC2)C([C@](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@]3([H])N1CCC3)=O)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)CC8=CC=CC=C8)=O)NC([C@H]9N(CCC9)C([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)CO)=O)([H])[C@@H](C)CC)=O
Biological Activity: VIR-165 is a modified form of virus inhibitory peptide (VIRIP) that binds the fusion peptide of the gp41 subunit and prevents its insertion into the target membrane. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains[1].
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VIR-165 | VIR-165 is a modified form of virus inhibitory peptide (VIRIP) that binds the fusion peptide of the gp41 subunit and prevents its insertion into the target membrane. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains. | |||||||||||||||||||||
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Keywords
