AKT-IN-21
AKT-IN-21 (compound C36) is a potent AKT inhibitor with broad-spectrum cytotoxicity and anticancer activity. AKT-IN-21 also blocks the cell cycle and induces apoptosis of cancer cells by down-regulating the PI3K/AKT pathway.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C26H34N2O4
- Molecular Weight:438.56
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
AKT-IN-21 shows anti-proliferation inhibitory activity and cytotoxcity among serval cancer cells, with IC50s of 2.33 μM (LNCaP), 2.38 μM (K562), 1.98 μM (HepG2), 3.95 μM (LX-2), respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 438.56
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Formel C26H34N2O4
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SMILES
COC1=C(C(/C=C/C2=CN=CC=C2)=O)C(O)=C(C/C=C(C)/C)C(OCCN(CC)CC)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)