country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-181518

Copy Link Print Information

c-Kit-IN-15

c-Kit-IN-15 is a c-Kit inhibitor. c-Kit-IN-15 inhibits the c-Kit signaling pathway and suppresses cancer cell proliferation. c-Kit-IN-15 can be used in research related to hepatocellular carcinoma and breast cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₉H₅₅NO₃
Molecular Weight:585.86

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

c-Kit-IN-15 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

c-Kit-IN-15 (Compound I9) (10 μM, 48 h) potently inhibits the proliferation of HepG-2 and MCF-7 cells, with IC₅₀ values of 8.94 μM and 9.64 μM, respectively^[1].
c-Kit-IN-15 (3-9 μM) downregulates the expression of c-Kit protein in MCF-7 cells in a concentration-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

human hepatocellular carcinoma HepG-2 cells, human breast cancer MCF-7 cells
Concentration:

10 μM; tested for IC₅₀ determination
Incubation Time:

48 h
Result:

Inhibited HepG-2 cell proliferation by 55.29% and MCF-7 cell proliferation by 50.44%.
Exhibited an IC₅₀ of 8.94 μmol/L in HepG-2 cells and 9.64 μmol/L in MCF-7 cells.

Chemical Information

Molecular Weight 585.86
Formel C₃₉H₅₅NO₃
SMILES

O=C([C@]12CCC(C)(CC1C3=CCC4[C@]5(C=CC(C(C)(C5CC[C@]4([C@@]3(CC2)C)C)C)=O)C)C)OCCNC6=CC=CC(C)=C6
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhou X, et al. Design, synthesis, and antitumor activity study of novel oleanolic acid structural derivatives targeting c-Kit. Bioorg Med Chem Lett. Published online October 10, 2025. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen