Based on 1 Customer Validation
Cholesterol (GMP Like, synthetic) is Cholesterol (synthetic) (HY-N0322E) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Cholesterol (synthetic) is a synthetic form of cholesterol. It is a lipid that sustains vital functions. Cholesterol (synthetic) can be used in research on cardiovascular diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.89%
- CAS. Nr.: 57-88-5
- Formel: C27H46O
- Molecular Weight:386.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>20 μM
Compound: b1
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 30822712] |
| BJ | IC50 |
>50 μM
Compound: Cholesterol
|
Cytotoxicity against human BJ cells after 72 hrs by calcein AM assay
Cytotoxicity against human BJ cells after 72 hrs by calcein AM assay
|
[PMID: 22417637] |
| CCRF-CEM | IC50 |
>50 μM
Compound: Cholesterol
|
Cytotoxicity against human CEM cells after 72 hrs by calcein AM assay
Cytotoxicity against human CEM cells after 72 hrs by calcein AM assay
|
[PMID: 22417637] |
| HeLa | IC50 |
>50 μM
Compound: Cholesterol
|
Cytotoxicity against human HeLa cells after 72 hrs by calcein AM assay
Cytotoxicity against human HeLa cells after 72 hrs by calcein AM assay
|
[PMID: 22417637] |
| HL-60 | IC50 |
>20 μM
Compound: b1
|
Antiproliferative activity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 30822712] |
| HT-29 | IC50 |
>50 μM
Compound: 1
|
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar Blue assay
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar Blue assay
|
[PMID: 19473028] |
| MCF7 | IC50 |
>20 μM
Compound: b1
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 30822712] |
| MCF7 | IC50 |
>50 μM
Compound: Cholesterol
|
Cytotoxicity against human MCF7 cells after 72 hrs by calcein AM assay
Cytotoxicity against human MCF7 cells after 72 hrs by calcein AM assay
|
[PMID: 22417637] |
| SMMC-7721 | IC50 |
>20 μM
Compound: b1
|
Antiproliferative activity against human SMMC7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human SMMC7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 30822712] |
| SW480 | IC50 |
>20 μM
Compound: b1
|
Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 30822712] |
| Vero | IC50 |
>128 μg/mL
Compound: 6
|
Cytotoxicity against african green monkey Vero cells
Cytotoxicity against african green monkey Vero cells
|
[PMID: 18818073] |
Chemical Information
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CAS. Nr. 57-88-5
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Appearance Solid
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Molecular Weight 386.65
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Formel C27H46O
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Color White to off-white
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SMILES
O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CCCC(C)C)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)