Nbea - neurobeachin Gene

Also Known as Lyst2; mKIAA1544

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26422

Summary

Enables protein kinase binding activity. Acts upstream of or within hematopoietic stem cell homeostasis and protein localization. Located in several cellular components, including cytosol; nucleus; and trans-Golgi network. Is expressed in several structures, including brain; branchial arch; neural tube; sensory organ; and somite. Used to study autism spectrum disorder. Orthologous to human NBEA (neurobeachin). [provided by Alliance of Genome Resources, Apr 2022]

Nbea Products (1)

mRNA Protein Name
NM_030595.1 NP_085098.1 neurobeachin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein kinase binding IDA
IDA: Inferred from direct assay
11102458 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within hematopoietic stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
26880577 MGI
acts upstream of or within protein localization IDA
IDA: Inferred from direct assay
11102458 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
29847800 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
29847800 MGI
involved in synapse organization IDA
IDA: Inferred from direct assay
22109531 MGI
involved in synapse organization IMP
IMP: Inferred from mutant phenotype
22109531 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytosol IDA
IDA: Inferred from direct assay
11102458 MGI
located in endomembrane system IDA
IDA: Inferred from direct assay
11102458 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22109531 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22109531 MGI
located in nucleus IDA
IDA: Inferred from direct assay
26999814 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11102458 MGI
located in trans-Golgi network IDA
IDA: Inferred from direct assay
11102458 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurobeachin

  • lysosomal trafficking regulator 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-174458 MD-4251 Degrader / Unkown
HY-RS09053 NBEA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21387 Nbea Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27906 Nbea Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nbea NCBI NCBI:26960