Usp19 - ubiquitin specific peptidase 19 Gene

Also Known as Zmynd9; 8430421I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71472

Summary

Enables Lys48-specific Deubiquitinase activity; thiol-dependent deubiquitinase; and ubiquitin protein Ligase binding activity. Involved in several processes, including negative regulation of proteasomal protein catabolic process; protein K48-linked deubiquitination; and protein stabilization. Located in cytosol. Is expressed in ovary and primary sex cord. Orthologous to human USP19 (ubiquitin specific peptidase 19). [provided by Alliance of Genome Resources, Apr 2022]

Usp19 Products (5)

mRNA Protein Name
NM_001168371.2 NP_001161843.1 ubiquitin carboxyl-terminal hydrolase 19 isoform 2
NM_001168372.2 NP_001161844.1 ubiquitin carboxyl-terminal hydrolase 19 isoform 3
NM_001168373.2 NP_001161845.1 ubiquitin carboxyl-terminal hydrolase 19 isoform 4
NM_027804.4 NP_082080.3 ubiquitin carboxyl-terminal hydrolase 19 isoform 1
NM_145407.3 NP_663382.2 ubiquitin carboxyl-terminal hydrolase 19 isoform 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables K48-linked deubiquitinase activity IDA
IDA: Inferred from direct assay
25088257 MGI
enables cysteine-type deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
21971047 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25036637 MGI
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
25088257 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of proteasomal protein catabolic process IDA
IDA: Inferred from direct assay
25088257 MGI
involved in negative regulation of skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
21971047 MGI
involved in protein K48-linked deubiquitination IDA
IDA: Inferred from direct assay
25088257 MGI
involved in protein stabilization IDA
IDA: Inferred from direct assay
25088257 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytosol IDA
IDA: Inferred from direct assay
19015242 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 19

  • deubiquitinating enzyme 19

  • ubiquitin specific protease 19

  • ubiquitin thioesterase 19

  • ubiquitin thiolesterase 19

  • ubiquitin-specific processing protease 19

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15529 USP19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18413 Usp19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24894 Usp19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp19 NCBI NCBI:10869