IHMT-RAF-128
IHMT-RAF-128, a highly potent pan-RAF inhibitor. IHMT-RAF-128 shows potent antitumor efficacy in xenograft mouse tumor models without causing any apparent toxicities.
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- CAS. Nr.: 2479289-15-9
- Formel: C27H24F3N5O2
- Molecular Weight:507.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2479289-15-9
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Molecular Weight 507.51
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Formel C27H24F3N5O2
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SMILES
FC(F)(F)C1=CC(C(NC2=CC(N3N=CC(C4=CC(N5CCOCC5)=CN=C4)=C3)=C(C)C=C2)=O)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Olaoba OT, et al. Driver Mutations in Pancreatic Cancer and Opportunities for Targeted Therapy. Cancers (Basel). 2024 May 9;16(10):1808. [Content Brief]
[2]. Wang A, et al. Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment. Eur J Pharmacol. 2023 Aug 5;952:175752. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
IHMT-RAF-128 Related Classifications
HY-164484 Related Classifications
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