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Art. -Nr.: HY-186182

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PF-1010

PF-1010 is a CD73 inhibitor with an IC₅₀ ranging from 101 to 1000 nM. PF-1010 blocks the interaction between CD73 protein and its substrate, and inhibits the enzymatic activity of CD73. PF-1010 is applicable to the research of cancer, infectious diseases, autoimmune diseases and neurodegenerative diseases.

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CAS. Nr.: 2653350-02-6
Formel: C₃₄H₂₇ClF₃N₃O₆
Molecular Weight:666.04

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PF-1010 Chemical Structure

CAS. Nr.: 2653350-02-6

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biologische Aktivität

Beschreibung

Chemical Information

CAS. Nr. 2653350-02-6
Molecular Weight 666.04
Formel C₃₄H₂₇ClF₃N₃O₆
SMILES

N#CC(C=C1)=CC=C1COC(C=C(C(Cl)=C2)NCC3=C(C(C4=CC=C(C=C4)OC(F)(F)F)=CC=C3)C)=C2CN5[C@H](COC5=O)C(O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Geng, et al. Small molecule non-nucleoside compound as immunomodulator. CN112920132A.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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