(±)15-HEDE
(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 77159-57-0
- Formel: C20H36O3
- Molecular Weight:324.50
-
Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
-
HY-120255
17(R)-HDHADecomposition-promoting Media -
HY-120891
trans-EKODE-(E)-IbPeroxide -
HY-115701
1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-PePhospholipid -
HY-130309
(±)8(9)-EpETEEpoxide -
HY-150084
(±)14,15-Epoxyeicosatrienoic acidProliferation Inducer -
HY-130140
8,9-DiHETEEster Product -
HY-130138C
5,6-DiHETEAnti-inflammatory Lipid Mediators -
HY-113490
15-KETE -
HY-113438
15(S)-HPETEProduct Of Arachidonic Acid -
HY-130675A
15(S)-HEPEAsthma Marker -
HY-113434
5(S)-HETEEndogenous Metabolite -
HY-124404A
12(S)-HETEP38 MAPK/ERK Activator
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
35 μM
Compound: 16
|
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
|
[PMID: 3806609] |
Chemical Information
-
CAS. Nr. 77159-57-0
-
Appearance Liquid
-
Molecular Weight 324.50
-
Formel C20H36O3
-
Color Colorless to light yellow
-
SMILES
CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Protokoll
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
-
Data Sheet (261 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(±)15-HEDE Related Classifications
HY-121987A Related Classifications
Powered by Bioz