country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

13 Results for "

NMB-R

" in MedChemExpress (MCE) Product Catalog:

Products (13)

Sort by :

Categories

By Targets

Products

BIM 23042 TFA

1 Cited Publications

Art. -Nr.: HY-103277A

Reinheit: 96.20%

Target:

Bombesin Receptor

Forschungsgebiete:

Neurological Disease Metabolic Disease

BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca ²⁺ release .

Compare

Please select quantity

August 31

Angebot einholen

View All Sizes

Advantame

Art. -Nr.: HY-122351A

CAS. Nr.: 714229-20-6

Reinheit: 99.66%

Target:

Taste Receptor

Forschungsgebiete:

Others

Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K ⁺ channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .

Compare

Please select quantity

August 31

Angebot einholen

View All Sizes

PD 168368

Art. -Nr.: HY-116216

CAS. Nr.: 204066-82-0

Reinheit: 98.78%

Target:

Bombesin Receptor

Forschungsgebiete:

Cancer

PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the K_i of 15–45 nM . PD 168368 is neuromedin B receptor (NMBR; IC₅₀=96 nM) / gastrin-releasing peptide receptor (GRPR IC₅₀=3500 nM) antagonist . PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC₅₀s of 0.57, 0.24, and 2.7 nM, respectively .

Compare