DNMT2-IN-1
DNMT2-IN-1 (compound 80) is a potent and selective DNMT2 (DNA methyltransferase 2) inhibitor with an IC50 value of 1.2 μM, and has the potential for mental and metabolic disorders or cancer research.
For research use only. We do not sell to patients.
- Formula: C20H23BrN8O9S.3/2C2HF3O2
- Molecular Weight:803.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All DNA Methyltransferase Isoforms
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Biological Activity
Description
IC50 & Target
DNA methyltransferase 2 (DNMT2) [1] IC50:1.2 μM (DNA methyltransferase 2,DNMT2)[1]
In Vitro
DNMT2-IN-1 (compound 80) (100 μM) inhibits hDNMT2 with inhibitory rate of 98.7%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 803.45
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Formula C20H23BrN8O9S.3/2C2HF3O2
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SMILES
N[C@H](C(O)=O)CCN(S(=O)(C1=CC([N+]([O-])=O)=C(Br)C=C1)=O)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(N=C3)C(N)=NC=N4)O)O.O=C(O)C(F)(F)F.[3/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DNMT2-IN-1 Related Classifications
HY-154867 Related Classifications
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