2. Cell Cycle/DNA Damage Anti-infection Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis HCV HCV Protease
  4. CID-50930756

CID-50930756 is an HCV NS3 helicase inhibitor with an IC50 of 22 μM.CID-50930756 inhibits HCV NS3 helicase-catalyzed nucleic acid unwinding.CID-50930756 inhibits HCV replication in hepatoma cells harboring a stably transfected subgenomic HCV replicon.CID-50930756 does not exhibit toxicity to hepatoma cells at 10 μM.CID-50930756 shows weak DNA-binding activity, displacing less than 20% of SYBR Green I from DNA at 100 μM.CID-50930756 can be used for the research of hepatitis c.

For research use only. We do not sell to patients.

CID-50930756

CID-50930756 Chemical Structure

CAS No. : 1363454-18-5

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CID-50930756 Related Antibodies

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Description

CID-50930756 is an HCV NS3 helicase inhibitor with an IC50 of 22 μM.CID-50930756 inhibits HCV NS3 helicase-catalyzed nucleic acid unwinding.CID-50930756 inhibits HCV replication in hepatoma cells harboring a stably transfected subgenomic HCV replicon.CID-50930756 does not exhibit toxicity to hepatoma cells at 10 μM.CID-50930756 shows weak DNA-binding activity, displacing less than 20% of SYBR Green I from DNA at 100 μM.CID-50930756 can be used for the research of hepatitis c[1].

IC50 & Target

Helicase

 

In Vitro

CID-50930756 (Compound 31) (100 μM) exhibits weak DNA-binding activity, displacing 15% of SYBR Green I bound to DNA at a concentration of 100 μM[1].
CID-50930756 (10 μM; 72 h) inhibits the replication of HCV genotype 1b subgenomic replicons in Huh7.5 cells, with an inhibition rate of 51% after treatment with 10 μM for 72 h, and no cytotoxicity is observed[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CID-50930756 Related Antibodies
Molecular Weight

558.65

Formula

C27H18N4O4S3
CAS No.
SMILES

O=C(NC1=CC=C(C=C1)C2=NC3=CC=C(C=C3S2)C4=NC=5C=CC(=C(C5S4)S(=O)(=O)O)C)C=6C=NC=CC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CID-50930756 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CID-509307561363454-18-5CID50930756CID 50930756DNA/RNA SynthesisHCVHCV ProteaseHepatitis C virushepatoma cellsDNA-binding activityHuh7.5 cellsHCV NS3 helicaseHCV genotype 1bSYBR Green Isubgenomic HCV repliconHCV replicationnucleic acid unwindinghepatitis cInhibitorinhibitorinhibit

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