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Cat. No.: HY-115768R

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Compound 48/80 (Standard)

Name: Compound 48/80 (Standard)
Brand: MedChemExpress
SKU: HY-115768R
Availability: PreOrder

(Synonyms: Poly-p-methoxyphenethylmethylamine (Standard))

Compound 48/80 (Standard) is the analytical standard of Compound 48/80 (HY-115768). This product is intended for research and analytical applications. Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways.

For research use only. We do not sell to patients.

CAS No.: 94724-12-6
Formula: C₃₂H₄₅N₃O₃
Molecular Weight:519.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Compound 48/80 (Standard) Chemical Structure

CAS No.: 94724-12-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 94724-12-6
Molecular Weight 519.72
Formula C₃₂H₄₅N₃O₃
SMILES

CNCCC1=CC(CC2=CC(CCNC)=CC=C2OC)=C(OC)C(CC3=CC(CCNC)=CC=C3OC)=C1
Synonyms

Poly-p-methoxyphenethylmethylamine (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Schemann M, et al. The mast cell degranulator compound 48/80 directly activates neurons. PLoS One. 2012;7(12):e52104. [Content Brief]

[2]. Wang YH, Taché Y, Harris AG, Kreutner W, Daly AF, Wei JY. Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy. 2005;60(1):117-124. [Content Brief]

[3]. Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. J Cell Physiol. 1984;119(1):1-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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