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ACBD3 - acyl-CoA binding domain containing 3 Gene

Also Known as PAP7; GCP60; GOCAP1; GOLPH1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 64746

About ACBD3

Cytogenetic location: 1q42.12 Genomic coordinates (GRCh38): 1:226,144,679-226,186,741 (from NCBI)

This gene has 2 transcripts (splice variants), 229 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 19.9), esophagus (RPKM 18.2) and 25 other tissues.

Summary

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008]

ACBD3 Products (1)

mRNA	Protein	Name
NM_022735.4	NP_073572.2	Golgi resident protein GCP60

ACBD3 Protein Structure

ACBP

GOLD_2

0
100
200
300
400
500
528 a.a.

Protein Preferred Names	Protein Names
Golgi resident protein GCP60	PBR- and PKA-associated protein 7

ACBD3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ACBD3	Q9H3P7	PI4KB	Homo sapiens	Q9UBF8	IF	22124328
Intra	ACBD3	Q9H3P7	PI4KB	Homo sapiens	A0A0B4J1S8	Gal4 VP16 Complement	23572552
Intra	ACBD3	Q9H3P7	PI4KB	Homo sapiens	A0A0B4J1S8	Pull Down	23572552
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448015	Aichi virus A846/88	O91464-PRO_0000448015	Pull Down	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448015	Aichi virus A846/88	O91464-PRO_0000448015	Y2H	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448015	Aichi virus A846/88	O91464-PRO_0000448015	Anti Tag CoIP	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448012	Aichi virus A846/88	O91464-PRO_0000448012	Anti Tag CoIP	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448012	Aichi virus A846/88	O91464-PRO_0000448012	Y2H	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448012	Aichi virus A846/88	O91464-PRO_0000448012	Pull Down	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448014	Aichi virus A846/88	O91464-PRO_0000448014	Pull Down	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448014	Aichi virus A846/88	O91464-PRO_0000448014	Y2H	22124328
Cross	ACBD3	Q9H3P7	O91464-PRO_0000448014	Aichi virus A846/88	O91464-PRO_0000448014	Anti Tag CoIP	22124328
Intra	ACBD3	Q9H3P7	TBC1D22A	Homo sapiens	Q8WUA7	Gal4 VP16 Complement	23572552
Intra	ACBD3	Q9H3P7	TBC1D22A	Homo sapiens	Q8WUA7	Pull Down	23572552
Cross	ACBD3	Q9H3P7	polg_aiva8	Aichi virus A846/88	O91464	Y2H	22124328
Cross	ACBD3	Q9H3P7	polg_aiva8	Aichi virus A846/88	O91464	Gal4 VP16 Complement	23572552
Cross	ACBD3	Q9H3P7	polg_aiva8	Aichi virus A846/88	O91464	Anti Tag CoIP	22124328
Cross	ACBD3	Q9H3P7	polg_aiva8	Aichi virus A846/88	O91464	Pull Down	23572552
Cross	ACBD3	Q9H3P7	Ppm1l	Mus musculus	Q8BHN0	IF	22796112
Cross	ACBD3	Q9H3P7	Ppm1l	Mus musculus	Q8BHN0	Y2H	22796112
Intra	ACBD3	Q9H3P7	TBC1D22B	Homo sapiens	Q9NU19	Gal4 VP16 Complement	23572552
Intra	ACBD3	Q9H3P7	TBC1D22B	Homo sapiens	Q9NU19	Pull Down	23572552
Cross	ACBD3	Q9H3P7	P03300-PRO_0000424692	Poliovirus type 1	P03300-PRO_0000424692	Gal4 VP16 Complement	23572552
Cross	ACBD3	Q9H3P7	P03300-PRO_0000424692	Poliovirus type 1	P03300-PRO_0000424692	Pull Down	23572552
Cross	ACBD3	Q9H3P7	Q66282-PRO_0000039600	Coxsackievirus B3	Q66282-PRO_0000039600	Pull Down	23572552

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Nonparalytic Poliomyelitis	Acute Nonparalytic Poliomyelitis Non-Paralytic Aseptic Meningitis
Schizophrenia 14	Sczd14 Schizophrenia, Susceptibility To, 14 Schizophrenia Susceptibility Locus, Chromosome 2q32-Related
Nasal Cavity Lymphoma	Lymphoma Of Nasal Cavity Lymphoma Of The Nasal Cavity
Acute Flaccid Myelitis
Poliomyelitis	Polio Infantile Paralysis
Acute Hemorrhagic Conjunctivitis	Viral Conjunctivitis Conjunctivitis, Acute Hemorrhagic Apollo Disease Epidemic Hemorrhagic Conjunctivitis Viral Conjunctiva Disorder Viral Conjunctivitis Nos
Primary Pigmented Nodular Adrenocortical Disease	Ppnad Primary Pigmented Nodular Adrenal Dysplasia Pigmented Nodular Adrenocortical Disease, Primary, 2 Pigmented Nodular Adrenocortical Disease, Primary, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00142	ACBD3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ACBD3	VGNC	VGNC:59500
Bos taurus	ACBD3	VGNC	VGNC:25531
Canis familiaris	ACBD3	VGNC	VGNC:37500
Mus musculus	ACBD3	MGD	MGI:2181074
Rattus norvegicus	ACBD3	RGD	RGD:727851
Macaca mulatta	ACBD3	VGNC	VGNC:69408
Others	ACBD3	NCBI