EGFR/VEGFR2-IN-7
EGFR/VEGFR2-IN-7 (Compound 3e) is a dual-target EGFR/VEGFR2 inhibitor, with IC50 values of 142 (EGFR) and 71 nM (VEGFR2). EGFR/VEGFR2-IN-7 exhibits broad-spectrum and potent anti-proliferative activity, especially being sensitive to breast cancer. EGFR/VEGFR2-IN-7 induces cell cycle arrest and apoptosis, inhibits cell migration and invasion. EGFR/VEGFR2-IN-7 can be used for research on breast cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C25H24N2O3
- Peso molecular:400.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Ver todos los productos específicos de isoformas EGFR
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Actividad biológica
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EGFR 142 nM (IC50) |
VEGFR2 71 nM (IC50) |
Chemical Information
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Peso molecular 400.47
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Fòrmula C25H24N2O3
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SMILES
O=C(C)N1C(C2=CC=C(OC)C=C2)CC(C(C=C3)=CC=C3OCC4=CC=CC=C4)=N1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/VEGFR2-IN-7 Related Classifications
HY-179031 Related Classifications
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