EGFR/VEGFR2-IN-7
EGFR/VEGFR2-IN-7 (Compound 3e) is a dual-target EGFR/VEGFR2 inhibitor, with IC50 values of 142 (EGFR) and 71 nM (VEGFR2). EGFR/VEGFR2-IN-7 exhibits broad-spectrum and potent anti-proliferative activity, especially being sensitive to breast cancer. EGFR/VEGFR2-IN-7 induces cell cycle arrest and apoptosis, inhibits cell migration and invasion. EGFR/VEGFR2-IN-7 can be used for research on breast cancer.
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- 화학식: C25H24N2O3
- 분자량:400.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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EGFR 142 nM (IC50) |
VEGFR2 71 nM (IC50) |
Chemical Information
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분자량 400.47
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화학식 C25H24N2O3
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SMILES
O=C(C)N1C(C2=CC=C(OC)C=C2)CC(C(C=C3)=CC=C3OCC4=CC=CC=C4)=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/VEGFR2-IN-7 Related Classifications
HY-179031 Related Classifications
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