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Referencia número: HY-42849

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Sultopride

Name: Sultopride
Brand: MedChemExpress
SKU: HY-42849
Availability: PreOrder

(Synonyms: LIN-1418)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.

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No. CAS: 53583-79-2
Fòrmula: C₁₇H₂₆N₂O₄S
Peso molecular:354.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Sultopride Chemical Structure

No. CAS: 53583-79-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.

IC₅₀ & Target

Dopamine D2 receptor^[1]

Ver todos los productos específicos de isoformas Dopamine Receptor :

In Vivo

Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 53583-79-2
Peso molecular 354.46
Fòrmula C₁₇H₂₆N₂O₄S
SMILES

O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC
Synonyms

LIN-1418
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Acta Pharmacol Sin

Isosibiricin inhibits microglial activation by targeting the dopamine D1/D2 receptor-dependent NLRP3/caspase-1 inflammasome pathway. [Abstract]

2020 Feb;41(2):173-180. PMID: 31506572

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Sultopride

1 Cited Publications

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Sultopride

Publications Citing Use of MedChemExpress (MCE) Sultopride

Ver todos los productos específicos de isoformas Dopamine Receptor