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Cat. No.: HY-W766548

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Floxuridine-¹³C,¹⁵N₂

(Synonyms: 5-Fluorouracil 2'-deoxyriboside-¹³C,¹⁵N₂)

Floxuridine-¹³C,¹⁵N₂ (5-Fluorouracil 2'-deoxyriboside-¹³C,¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled Floxuridine (HY-B0097). Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis. Floxuridine has antiviral effects against HSV and CMV.

For research use only. We do not sell to patients.

Formula: C₈¹³CH₁₁F¹⁵N₂O₅
Molecular Weight:249.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (244 KB)

Floxuridine-¹³C,¹⁵N₂ Chemical Structure

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Biological Activity

Description

Floxuridine-¹³C,¹⁵N₂ (5-Fluorouracil 2'-deoxyriboside-¹³C,¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled Floxuridine (HY-B0097). Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis^[1]^[2]. Floxuridine has antiviral effects against HSV and CMV^[3].

All DNA/RNA Synthesis Isoforms :

All HSV Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 50-91-9
Molecular Weight 249.17
Formula C₈¹³CH₁₁F¹⁵N₂O₅
SMILES

O[C@H]1C[C@@H](O[C@@H]1CO)[15N](C=C2F)[13C]([15NH]C2=O)=O
Synonyms

5-Fluorouracil 2'-deoxyriboside-¹³C,¹⁵N₂
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.