COX-2-IN-65
COX-2-IN-65 is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 10.24 μM. COX-2-IN-65 inhibits Staphylococcus aureus and Escherichia coli growth. COX-2-IN-65 scavenges reactive oxygen species (ROS). COX-2-IN-65 can be used for the researches of bacterial infections and inflammation.
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- No. CAS: 1408337-43-8
- Fòrmula: C18H14ClNO3
- Peso molecular:327.76
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
COX-2 10.24 μM (IC50) |
In Vitro
COX-2-IN-65 (Compound 4h) selectively inhibits recombinant human COX-2 with an IC50 of 10.24 μM and a selectivity index of 3.09[1].
COX-2-IN-65 inhibits 30% of Staphylococcus aureus growth and 90% of Escherichia coli growth[1].
COX-2-IN-65 (50-100 μg/mL) shows ROS-scavenging capacity (37-61%)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1408337-43-8
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Peso molecular 327.76
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Fòrmula C18H14ClNO3
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SMILES
CCOC(C1=C2N(C(C(C3=CC=CC=C3)=O)=C1)C=CC(Cl)=C2)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-65 Related Classifications
HY-181144 Related Classifications
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