Akap3 - A kinase (PRKA) anchor protein 3 Gene

Also Known as Prka3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11642

Summary

Enables protein kinase A binding activity. Acts upstream of or within blastocyst hatching; protein localization; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in acrosomal vesicle; sperm fibrous sheath; and sperm principal piece. Is expressed in early conceptus; secondary oocyte; and spermatocyte. Orthologous to human AKAP3 (A-kinase anchoring protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Akap3 Products (1)

mRNA Protein Name
NM_009650.2 NP_033780.2 A-kinase anchor protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
12606363 MGI
enables protein kinase A binding IMP
IMP: Inferred from mutant phenotype
10319321 MGI
Biological Process GO Annotation Evidence Referencias Source
acts upstream of or within blastocyst hatching IMP
IMP: Inferred from mutant phenotype
27869233 MGI
acts upstream of or within cell surface receptor protein serine/threonine kinase signaling pathway IPI
IPI: Inferred from physical interaction
10319321 MGI
involved in establishment of protein localization IMP
IMP: Inferred from mutant phenotype
31969357 MGI
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
31969357 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
10319321 MGI
acts upstream of or within sperm motility IMP
IMP: Inferred from mutant phenotype
10319321 MGI
Cellular Component GO Annotation Evidence Referencias Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
11278869 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
12606363 MGI
is active in sperm fibrous sheath IDA
IDA: Inferred from direct assay
31969357 MGI
located in sperm fibrous sheath IDA
IDA: Inferred from direct assay
16687649 MGI
located in sperm principal piece IDA
IDA: Inferred from direct assay
11278869 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 3

  • A-kinase anchor protein 110 kDa

  • AKAP 110

  • AKAP-3

  • Protein kinase A-anchoring protein 3

Akap3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Referencias
Intra
Akap3 O88987 Brap Mus musculus Q99MP8
IF
25820252
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS00518 AKAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap3 NCBI NCBI:10566