Malformin A1
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9.
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- No. CAS: 3022-92-2
- Fòrmula: C23H39N5O5S2
- Peso molecular:529.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
0.76 μM
Compound: 1; synthetic
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
| U-937 | IC50 |
0.8 μM
Compound: 1; natural
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
Chemical Information
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No. CAS 3022-92-2
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Peso molecular 529.72
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Fòrmula C23H39N5O5S2
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Sequence Shortening
CCVLI (Disulfide bridge:Cys1-Cys2)
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)