TEAD-IN-23
TEAD-IN-23 (Compound 22) is an efficient pan-TEAD inhibitor with an IC50 of 10 nM. TEAD-IN-23 exhibits potent anti-proliferative activity in both NCI-H226 and MSTO-211H. TEAD-IN-23 causes complete tumor regression in the MSTO-211H xenograft tumor model. TEAD-IN-23 can be used for the study of mesothelioma and hepatocellular carcinoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3074990-47-6
- Fòrmula: C23H18ClF3N2O2
- Peso molecular:446.85
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
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Actividad biológica
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TEAD 0.01 μM (IC50) |
Chemical Information
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No. CAS 3074990-47-6
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Peso molecular 446.85
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Fòrmula C23H18ClF3N2O2
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SMILES
CC1=CC(C2=CN(C3=C2C(Cl)=NC=C3)CCO)=CC(OC4=CC=C(C=C4)C(F)(F)F)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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