2. Gene
  3. RAMP3 - receptor activity modifying protein 3 Gene

RAMP3 - receptor activity modifying protein 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 10268 | Gene type: protein coding

About RAMP3

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:45,157,791-45,184,250 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 2 paralogues. Broad expression in lung (RPKM 28.4), lymph node (RPKM 13.1) and 20 other tissues.

Summary

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (Calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an Adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an Adrenomedullin receptor. [provided by RefSeq, Jul 2008]

RAMP3 Products(1)

mRNA Protein Name
NM_005856.3 NP_005847.1 receptor activity-modifying protein 3 precursor

RAMP3 Protein Structure

RAMP

RAMP: Receptor activity modifying family (37 - 146)

  • 0
  • 100
  • 148 a.a.
Protein Preferred Names Protein Names

receptor activity-modifying protein 3

CRLR activity-modifying protein 3

Recombinant RAMP3 Proteins

Cat. No. Product Name Accession Purity
HY-P74603 RAMP3 Protein, Human (HEK293, hFc) O60896 (R24-V118) ≥95%

Related Diseases

Diseases Alias
Cartilage Cancer

Chondrogenic Neoplasm
Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11640 RAMP3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RAMP3 VGNC VGNC:33708
Canis familiaris RAMP3 VGNC VGNC:54348
Macaca mulatta RAMP3 VGNC VGNC:81750
Mus musculus RAMP3 MGD MGI:1860292
Rattus norvegicus RAMP3 RGD RGD:61873
Felis catus RAMP3 VGNC VGNC:102678
Others RAMP3 NCBI