Pan2 - PAN2 poly(A) specific ribonuclease subunit Gene

Also Known as Usp52; mKIAA0710; 1200014O24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103135

Summary

Predicted to enable poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within nuclear-transcribed mRNA catabolic process, exonucleolytic. Located in P-body. Is expressed in 1-cell stage embryo; 2-cell stage embryo; 4-cell stage embryo; primary oocyte; and secondary oocyte. Orthologous to human PAN2 (poly(A) specific ribonuclease subunit PAN2). [provided by Alliance of Genome Resources, Apr 2022]

Pan2 Products (4)

mRNA Protein Name
NM_001252326.1 NP_001239255.1 PAN2-PAN3 deadenylation complex catalytic subunit Pan2 isoform 2
NM_001252327.1 NP_001239256.1 PAN2-PAN3 deadenylation complex catalytic subunit Pan2 isoform 3
NM_001358822.1 NP_001345751.1 PAN2-PAN3 deadenylation complex catalytic subunit Pan2 isoform 4
NM_133992.3 NP_598753.1 PAN2-PAN3 deadenylation complex catalytic subunit Pan2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18625844 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
18625844 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PAN2-PAN3 deadenylation complex catalytic subunit Pan2

  • AN2 polyA specific ribonuclease subunit homolog

  • PAB-dependent poly(A)-specific ribonuclease subunit 2

  • PAB-dependent poly(A)-specific ribonuclease subunit PAN2

  • PAB1P-dependent poly(A)-nuclease

  • PAN deadenylation complex catalytic subunit 2

  • PAN2 polyA s

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09360 NLRP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10014 PAN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17294 Pan2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18501 Tcf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23749 Pan2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24983 Tcf3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pan2 NCBI NCBI:9924