Cyp27a1 - cytochrome P450, family 27, subfamily a, polypeptide 1 Gene

Also Known as Cyp27; 1300013A03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104086

Summary

Predicted to enable HSP70 protein binding activity; heme binding activity; and monooxygenase activity. Predicted to be involved in bile acid biosynthetic process; calcitriol biosynthetic process from calciol; and Cholesterol catabolic process. Predicted to act upstream of or within steroid biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; liver; male reproductive gland or organ; metanephros; and retina. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (Cytochrome P450 family 27 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp27a1 Products (1)

mRNA Protein Name
NM_024264.5 NP_077226.2 sterol 26-hydroxylase, mitochondrial precursor
Protein Preferred Names Protein Names

sterol 26-hydroxylase, mitochondrial

  • 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase

  • 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

  • cholesterol 27 hydroxylase

  • cytochrome P-450C27/25

  • cytochrome P450, 27a1

  • sterol 27-hydroxylase

  • vitamin D(3) 25-hydroxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130705A Tachysterol 3 99.68% Unkown
HY-16670 Dafadine-A Inhibitor 98.94% Unkown
HY-138115 7ß,27-Dihydroxycholesterol Activator 99.58% Unkown
HY-173191 SK-124 Inhibitor 95.0% Unkown
HY-154825 20-Hydroxyvitamin D3 ≥98.0% Unkown
HY-139067 25(S)-27-Hydroxy cholesterol Activator / Unkown
HY-176497 GW273297X Inhibitor / Unkown
HY-RS03450 CYP27A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03451 CYP27B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03452 CYP27C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16287 Cyp27b1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS17011 Cyp27a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23454 Cyp27a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25766 Cyp27b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp27a1 NCBI NCBI:1593