Csnk1d - casein kinase 1, delta Gene

Also Known as 1200006A05Rik; D930010H05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104318

Summary

This gene encodes a member of the Casein Kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and Hedgehog signaling pathways. The encoded protein may also be involved in the regulation of Apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Csnk1d Products (4)

mRNA Protein Name
NM_027874.3 NP_082150.1 casein kinase I isoform delta isoform 2
NM_139059.3 NP_620690.1 casein kinase I isoform delta isoform 1
NM_027874.3 NP_082150.1 casein kinase I isoform delta isoform 2
NM_139059.3 NP_620690.1 casein kinase I isoform delta isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19414593 MGI
enables protein kinase activity IDA
IDA: Inferred from direct assay
10848614 MGI
enables protein kinase activity IGI
IGI: Inferred from genetic interaction
17244647 MGI
enables protein kinase activity IMP
IMP: Inferred from mutant phenotype
29191835 MGI
Biological Process GO Annotation Evidence References Source
involved in circadian regulation of gene expression IMP
IMP: Inferred from mutant phenotype
19414593 MGI
involved in midbrain dopaminergic neuron differentiation IGI
IGI: Inferred from genetic interaction
17244647 MGI
acts upstream of or within non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
24648492 MGI
involved in positive regulation of Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
17027228 MGI
involved in positive regulation of non-canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
17244647 MGI
involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
19414593 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
19414593 MGI
involved in protein phosphorylation IGI
IGI: Inferred from genetic interaction
17027228 MGI
involved in protein phosphorylation IMP
IMP: Inferred from mutant phenotype
21930935 MGI
involved in regulation of circadian rhythm IMP
IMP: Inferred from mutant phenotype
19414593 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19414593 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

casein kinase I isoform delta

casein kinase I

  • CKI-delta

  • CKId

  • tau-protein kinase CSNK1D

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148233S JNJ-6204 99.75% Unkown
HY-137340 WH-10417-099 Degrader 98.14% Unkown
HY-184652 LRRK2/JNK3-IN-1 Inhibitor / Unkown
HY-RS03246 CSNK1D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21113 Csnk1d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27632 Csnk1d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Csnk1d NCBI NCBI:1453