2. Gene
  3. IFI30 - IFI30 lysosomal thiol reductase Gene

IFI30 - IFI30 lysosomal thiol reductase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GILT; IP30; IP-30; IFI-30

Gene ID: 10437 | Gene type: protein coding

About IFI30

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:18,173,813-18,178,117 (from NCBI)

This gene has 3 transcripts (splice variants) and 127 orthologues. Broad expression in appendix (RPKM 362.8), lung (RPKM 227.6) and 16 other tissues.

Summary

The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The Enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This Enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008]

IFI30 Products(1)

mRNA Protein Name
NM_006332.5 NP_006323.2 gamma-interferon-inducible lysosomal thiol reductase preproprotein

IFI30 Protein Structure

GILT

GILT: Gamma interferon inducible lysosomal thiol reductase (GILT) (62 - 164)

  • 0
  • 100
  • 200
  • 250 a.a.
Protein Preferred Names Protein Names

gamma-interferon-inducible lysosomal thiol reductase

gamma-interferon-inducible protein IP-30

Recombinant IFI30 Proteins

Cat. No. Product Name Accession Purity
HY-P75820 IFI30 Protein, Human (HEK293, His) P13284 (S27-K243) ≥95%

Related Diseases

Diseases Alias
Lassa Fever

Lf

Lassa Hemorrhagic Fever

Lf - [Lassa Fever]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06554 IFI30 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IFI30 RGD RGD:1310758
Mus musculus IFI30 MGD MGI:2137648
Felis catus IFI30 VGNC VGNC:67696
Canis familiaris IFI30 VGNC VGNC:41871
Bos taurus IFI30 VGNC VGNC:30043
Others IFI30 NCBI