Tafa5 - TAFA chemokine like family member 5 Gene

Also Known as Tafa-5; Tara-5; Fam19a5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 106014

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Tafa5 Products (2)

mRNA Protein Name
NM_001252310.1 NP_001239239.1 chemokine-like protein TAFA-5 isoform 1 precursor
NM_134096.2 NP_598857.1 chemokine-like protein TAFA-5 isoform 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
29453251 MGI
acts upstream of or within negative regulation of vascular wound healing IDA
IDA: Inferred from direct assay
29453251 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
31543758 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
29453251 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chemokine-like protein TAFA-5

  • family with sequence similarity 19, member A5

  • protein FAM19A5

Recombinant Tafa5 Proteins

Cat. No. Product Name Accession Purity
HY-P700985 TAFA5/FAM19A5 Protein, Mouse (His) Q91WE9-1 (T44-S132) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14183 TAFA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22846 Tafa5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tafa5 NCBI NCBI:25817