Eaf2 - ELL associated factor 2 Gene

Also Known as U19; Festa; Traits; FESTA-L; FESTA-S

Species: Mus musculus

Gene Type: protein coding
Gene ID: 106389

Summary

Predicted to enable transcription elongation regulator activity. Acts upstream of or within negative regulation of cell growth; negative regulation of epithelial cell proliferation involved in prostate gland development; and positive regulation of transcription, DNA-templated. Located in nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human EAF2 (ELL associated factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Eaf2 Products (4)

mRNA Protein Name
NM_001113401.1 NP_001106872.1 ELL-associated factor 2 isoform b
NM_001113405.1 NP_001106876.1 ELL-associated factor 2 isoform a
NM_001358102.1 NP_001345031.1 ELL-associated factor 2 isoform a
NM_134111.2 NP_598872.1 ELL-associated factor 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12761297 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cell growth IMP
IMP: Inferred from mutant phenotype
17873910 MGI
acts upstream of epithelial cell proliferation involved in prostate gland development IMP
IMP: Inferred from mutant phenotype
17873910 MGI
acts upstream of or within negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
17873910 MGI
acts upstream of or within negative regulation of epithelial cell proliferation involved in prostate gland development IMP
IMP: Inferred from mutant phenotype
17873910 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12761297 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleoplasm IDA
IDA: Inferred from direct assay
12761297 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ELL-associated factor 2

  • ehrlich S-II transcriptional activator factor

  • testosterone regulated apoptosis inducer and tumor suppressor

  • testosterone-regulated apoptosis inducer and tumor suppressor protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03819 DMAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04120 EAF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20724 Eaf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27236 Eaf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eaf2 NCBI NCBI:55840