Cenpf - centromere protein F Gene

Also Known as CENF; Lek1; PRO1779; mitosin; 6530404A22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108000

Summary

Predicted to enable several functions, including dynein complex binding activity; protein C-terminus binding activity; and protein homodimerization activity. Acts upstream of or within regulation of striated muscle tissue development. Located in Cytoskeleton and pronucleus. Part of ciliary transition fiber. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and limb. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F). [provided by Alliance of Genome Resources, Apr 2022]

Cenpf Products (1)

mRNA Protein Name
NM_001081363.2 NP_001074832.2 centromere protein F
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of striated muscle tissue development IDA
IDA: Inferred from direct assay
10373470 MGI
Cellular Component GO Annotation Evidence References Source
located in axoneme IDA
IDA: Inferred from direct assay
25564561 MGI
located in centrosome IDA
IDA: Inferred from direct assay
25564561 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
25564561 MGI
part of ciliary transition fiber IDA
IDA: Inferred from direct assay
25564561 MGI
NOT located in kinetochore IDA
IDA: Inferred from direct assay
10373470 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10373470 MGI
located in pronucleus IDA
IDA: Inferred from direct assay
10373470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centromere protein F

  • centromere autoantigen F

  • leucine, glutamic acid, lysine family 1 protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Cenpf NCBI NCBI:1063