Cpa1 - carboxypeptidase A1, pancreatic Gene

This gene encodes Carboxypeptidase A, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functional enzyme. This gene is expressed in pancreas, the encoded protein is a major component of digestive Enzymes secreted by pancreas and plays an important role in the process of digestion. This gene is located in a cluster of related Carboxypeptidase genes on chromosome 6. [provided by RefSeq, Jan 2016]