Aatk - apoptosis-associated tyrosine kinase Gene

Also Known as AATYK; aatyk1; mKIAA0641

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11302

Summary

Enables protein tyrosine kinase activity. Acts upstream of or within several processes, including Rab protein signal transduction; nervous system development; and peptidyl-tyrosine autophosphorylation. Located in several cellular components, including axonal growth cone; perinuclear region of cytoplasm; and recycling endosome. Is expressed in brain. Orthologous to human AATK (Apoptosis associated tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Aatk Products (5)

mRNA Protein Name
NM_001198785.1 NP_001185714.1 serine/threonine-protein kinase LMTK1 isoform 2 precursor
NM_001198787.1 NP_001185716.1 serine/threonine-protein kinase LMTK1 isoform 1
NM_001377503.1 NP_001364432.1 serine/threonine-protein kinase LMTK1 isoform 3
NM_001402789.1 NP_001389718.1 serine/threonine-protein kinase LMTK1 isoform 4
NM_007377.4 NP_031403.2 serine/threonine-protein kinase LMTK1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
11314040 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within apoptotic process IDA
IDA: Inferred from direct assay
9444961 MGI
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
22573681 MGI
acts upstream of or within neuron apoptotic process IDA
IDA: Inferred from direct assay
11314040 MGI
acts upstream of or within peptidyl-tyrosine autophosphorylation IDA
IDA: Inferred from direct assay
11314040 MGI
acts upstream of or within peptidyl-tyrosine autophosphorylation IMP
IMP: Inferred from mutant phenotype
11314040 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase LMTK1

  • apoptosis-associated tyrosine kinase 1B

  • brain apoptosis-associated tyrosine kinase

  • lemur tyrosine kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00035 AATK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22093 Aatk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28613 Aatk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aatk NCBI NCBI:9625