St14 - ST14 transmembrane serine protease matriptase Gene

Also Known as MT-SP1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114093

Summary

Enables serine-type peptidase activity. Involved in proteolysis. Located in basolateral plasma membrane and extracellular space. Is extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase). [provided by Alliance of Genome Resources, Apr 2022]

St14 Products (1)

mRNA Protein Name
NM_053635.2 NP_446087.1 suppressor of tumorigenicity 14 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
11573963 RGD
Biological Process GO Annotation Evidence References Source
involved in protein catabolic process IDA
IDA: Inferred from direct assay
11573963 RGD
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
15669920 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
15669920 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

suppressor of tumorigenicity 14 protein

  • matriptase

  • membrane-type serine protease

  • suppression of tumorigenicity 14 (colon carcinoma)

  • suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)

Orthologs Information

Species Symbol Source ID
Homo sapiens St14 NCBI NCBI:6768