Pax3 - paired box 3 Gene

Enables HMG box domain binding activity. Predicted to be involved in anatomical structure development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including animal organ development; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 1; Waardenburg syndrome type 3; Waardenburg's syndrome; alveolar rhabdomyosarcoma; and craniofacial-deafness-hand syndrome. Orthologous to human PAX3 (paired box 3). [provided by Alliance of Genome Resources, Apr 2022]