Adora2a - adenosine A2a receptor Gene

Mus musculus

Also known as A2aR; A2AAR; AA2AR; ARA2A

Gene ID: 11540 | Gene type: protein coding

About Adora2a

Chromosome 10: 75,152,711-75,170,618 forward strand.GRCm39:CM001003.3

This gene has 4 transcripts (splice variants), 263 orthologues, 3 paralogues and is associated with 42 phenotypes. Broad expression in thymus adult (RPKM 8.8), spleen adult (RPKM 8.) and 26 other tissues.

Summary

Enables G protein-coupled Adenosine Receptor activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; chemical synaptic transmission; and positive regulation of cell communication. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; intestine; and liver and biliary system. Used to study myopia and primary pulmonary hypertension. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA2A (adenosine A2a receptor). [provided by Alliance of Genome Resources, Apr 2022]

Adora2a Products(3)

mRNA	Protein	Name
NM_009630.3	NP_033760.2	adenosine receptor A2a
NM_001331095.1	NP_001318024.1	adenosine receptor A2a
NM_001331096.1	NP_001318025.1	adenosine receptor A2a

Adora2a Protein Structure

7tmA_Adenosine_R_A2A

0
100
200
300
410 a.a.

Protein Preferred Names

Protein Names

adenosine receptor A2a

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS00394	ADORA2A Human Pre-designed siRNA Set A	/	Unkown
HY-RS00395	Adora2a Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS00396	Adora2a Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adora2a	NCBI	NCBI:135

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