2. Gene
  3. Bak1 - BCL2-antagonist/killer 1 Gene

Bak1 - BCL2-antagonist/killer 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Bak

Gene ID: 116502 | Gene type: protein coding

About Bak1

Primary_assembly 20: 5,100,480-5,109,264 reverse strand.mRatBN7.2:CM026993.1

This gene has 1 transcript (splice variant), 135 orthologues, 13 paralogues and is associated with 15 phenotypes. Biased expression in Thymus (RPKM 137.4), Spleen (RPKM 16.9) and 9 other tissues.

Summary

Enables several functions, including chaperone binding activity; heat shock protein binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of release of cytochrome c from mitochondria; and release of cytochrome c from mitochondria. Located in cytosol; membrane; and mitochondrion. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1). [provided by Alliance of Genome Resources, Apr 2022]

Bak1 Products(1)

mRNA Protein Name
NM_053812.2 NP_446264.1 bcl-2 homologous antagonist/killer

Bak1 Protein Structure

Bcl-2_like

Bcl-2_like: cd06845 (26 - 180)

  • 0
  • 100
  • 209 a.a.
Protein Preferred Names Protein Names

bcl-2 homologous antagonist/killer

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01357 BAK1 Human Pre-designed siRNA Set A / Unkown
HY-RS01358 Bak1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS01359 Bak1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bak1 NCBI NCBI:578