Pdia4 - protein disulfide isomerase family A, member 4 Gene

Also Known as Erp70; Erp72; ERp-72

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116598

Summary

Enables protein disulfide isomerase activity. Involved in chaperone-mediated protein folding and positive regulation of protein folding. Located in smooth endoplasmic reticulum. Orthologous to human PDIA4 (protein disulfide isomerase family A member 4). [provided by Alliance of Genome Resources, Apr 2022]

Pdia4 Products (1)

mRNA Protein Name
NM_053849.2 NP_446301.2 protein disulfide-isomerase A4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
7916014 RGD
enables protein disulfide isomerase activity IDA
IDA: Inferred from direct assay
8477750 RGD
Biological Process GO Annotation Evidence References Source
involved in chaperone-mediated protein folding IDA
IDA: Inferred from direct assay
22665516 RGD
involved in positive regulation of protein folding IDA
IDA: Inferred from direct assay
16184766 RGD
Cellular Component GO Annotation Evidence References Source
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
22665516 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein disulfide-isomerase A4

  • ER protein 70

  • ER protein 72

  • caBP2

  • calcium-binding protein 2

  • endoplasmic reticulum resident protein 70

  • endoplasmic reticulum resident protein 72

  • protein disulfide isomerase associated 4

  • protein disulfide isomerase related protein (calcium-binding pr

Pdia4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Pdia4 P38659 Tg Rattus norvegicus P06882
Anti Bait CoIP
7916014
Intra
Pdia4 P38659 Ppib Rattus norvegicus P24368
Pull Down
22665516
Cross
Pdia4 P38659 Sep15 Drosophila melanogaster Q9VVJ7
Transcription Compl
22665516
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122895 E64FC26 98.48% Unkown
HY-122895A (E/Z)-E64FC26 99.80% Unkown
HY-RS10269 PDIA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17554 Pdia4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24012 Pdia4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdia4 NCBI NCBI:9601