SLC18B1 - solute carrier family 18 member B1 Gene

Also Known as C6orf192; dJ55C23.6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116843

About SLC18B1

Cytogenetic location: 6q23.2 Genomic coordinates (GRCh38): 6:132,769,370-132,798,637 (from NCBI)

This gene has 7 transcripts (splice variants), 214 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 13.1), duodenum (RPKM 8.9) and 25 other tissues.

Summary

This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008]

SLC18B1 Products (1)

mRNA Protein Name
NM_052831.3 NP_439896.1 MFS-type transporter SLC18B1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables monoamine:proton antiporter activity IDA
IDA: Inferred from direct assay
25355561 GOA
enables polyamine:proton antiporter activity IDA
IDA: Inferred from direct assay
25355561 GOA
Biological Process GO Annotation Evidence References Source
involved in serotonin uptake IDA
IDA: Inferred from direct assay
25355561 GOA
involved in spermidine transport IDA
IDA: Inferred from direct assay
25355561 GOA
involved in spermine transport IDA
IDA: Inferred from direct assay
25355561 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC18B1 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (44 - 237)

MFS_1

MFS_1: Major Facilitator Superfamily (251 - 439)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 456 a.a.
Protein Preferred Names Protein Names

MFS-type transporter SLC18B1

  • MFS-type transporter C6orf192

Related Diseases

Diseases Alias
Iminoglycinuria

  • Iminoglycinuria, Digenic

  • IG
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D3197 CDg16 / Unkown
HY-RS13046 SLC18B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22034 Slc18b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC18B1 VGNC VGNC:77549
Mus musculus SLC18B1 MGD MGI:1923556
Rattus norvegicus SLC18B1 RGD RGD:1306962
Bos taurus SLC18B1 VGNC VGNC:34708
Canis familiaris SLC18B1 VGNC VGNC:46258
Felis catus SLC18B1 VGNC VGNC:65228
Others SLC18B1 NCBI