Mark1 - microtubule affinity regulating kinase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117016

Summary

Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in several processes, including intracellular signal transduction; neuron migration; and protein phosphorylation. Located in cytoplasm and Cytoskeleton. Orthologous to human MARK1 (microtubule affinity regulating kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mark1 Products (1)

mRNA Protein Name
NM_053947.2 NP_446399.1 serine/threonine-protein kinase MARK1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
9108484 RGD
enables magnesium ion binding IDA
IDA: Inferred from direct assay
9108484 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
9108484 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9108484 RGD
enables tau-protein kinase activity IDA
IDA: Inferred from direct assay
9108484 RGD
Biological Process GO Annotation Evidence References Source
involved in cytoskeleton organization IDA
IDA: Inferred from direct assay
9108484 RGD
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
9108484 RGD
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
9108484 RGD
involved in neuron migration IDA
IDA: Inferred from direct assay
14741102 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9108484 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9108484 RGD
located in cytoskeleton IDA
IDA: Inferred from direct assay
9108484 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase MARK1

  • MAP/microtubule affinity-regulating kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139604 PCC0208017 99.52% Unkown
HY-120877 MRT199665 99.85% Unkown
HY-120877A (R)-MRT199665 98.70% Unkown
HY-RS08149 MARK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21640 Mark1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28158 Mark1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mark1 NCBI NCBI:4139