P2ry6 - pyrimidinergic receptor P2Y6 Gene

Rattus norvegicus

Also known as P2y6

Gene ID: 117264 | Gene type: protein coding

About P2ry6

Primary_assembly 1: 155,295,111-155,330,808 reverse strand.mRatBN7.2:CM026974.1

This gene has 5 transcripts (splice variants), 183 orthologues, 13 paralogues and is associated with 1 phenotype. Biased expression in Spleen (RPKM 12.8), Heart (RPKM 6.9) and 9 other tissues.

Summary

Predicted to enable G protein-coupled ADP receptor activity; G protein-coupled UDP receptor activity; and G protein-coupled UTP receptor activity. Involved in several processes, including cellular response to pyrimidine ribonucleotide; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; and positive regulation of smooth muscle cell migration. Located in apical plasma membrane and basolateral plasma membrane. Orthologous to human P2RY6 (pyrimidinergic receptor P2Y6). [provided by Alliance of Genome Resources, Apr 2022]

P2ry6 Products(1)

mRNA	Protein	Name
NM_057124.2	NP_476465.1	P2Y purinoceptor 6

P2ry6 Protein Structure

7tm_GPCRs

0
100
200
300
328 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 6

P2Y ATP receptor 6

pyrimidinergic receptor P2Y, G-protein coupled, 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09934	P2RY6 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09935	P2ry6 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09936	P2ry6 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry6	NCBI	NCBI:5031

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