Chd4 - chromodomain helicase DNA binding protein 4 Gene

Also Known as Mi-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117535

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; histone deacetylase binding activity; and transcription coregulator binding activity. Involved in negative regulation of transcription by RNA polymerase II and terminal button organization. Predicted to be located in centrosome; cytoplasm; and nucleoplasm. Predicted to be part of NuRD complex; RNA polymerase II transcription regulator complex; and protein-DNA complex. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Chd4 Products (7)

mRNA Protein Name
XM_006237396.4 XP_006237458.1 chromodomain-helicase-DNA-binding protein 4 isoform X1
XM_006237397.4 XP_006237459.1 chromodomain-helicase-DNA-binding protein 4 isoform X2
XM_006237401.4 XP_006237463.1 chromodomain-helicase-DNA-binding protein 4 isoform X3
XM_006237398.4 XP_006237460.1 chromodomain-helicase-DNA-binding protein 4 isoform X4
XM_006237400.4 XP_006237462.1 chromodomain-helicase-DNA-binding protein 4 isoform X7
XM_006237399.4 XP_006237461.1 chromodomain-helicase-DNA-binding protein 4 isoform X5
XM_232354.10 XP_232354.5 chromodomain-helicase-DNA-binding protein 4 isoform X6

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18456662 RGD
involved in regulation of synapse assembly IDA
IDA: Inferred from direct assay
24991957 RGD
involved in regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
24991957 RGD
involved in terminal button organization IMP
IMP: Inferred from mutant phenotype
24991957 RGD
Cellular Component GO Annotation Evidence References Source
is active in cerebellar granule cell to Purkinje cell synapse IDA
IDA: Inferred from direct assay
24991957 RGD
is active in cerebellar granule cell to Purkinje cell synapse IMP
IMP: Inferred from mutant phenotype
24991957 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromodomain-helicase-DNA-binding protein 4

  • Mi-2 autoantigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02609 CHD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18917 Chd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25407 Chd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chd4 NCBI NCBI:1108